Thermo Fisher Scientific Neurogranin Monoclonal Antibody (C2)
Neurogranin 단백질을 인식하는 C2 클론의 Mouse Monoclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. Human 시료 반응성. Recombinant Neurogranin(aa 1–67) 항원으로 제작. Protein A/G 정제, PBS+50% glycerol 저장.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–40 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C2 |
| Immunogen | Recombinant protein Neurogranin (aa 1–67 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899130 |
Target Information
Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium.
The NRGN gene contains four exons and three introns. Exons 1 and 2 encode the protein, while exons 3 and 4 contain untranslated sequences.
It is suggested that NRGN is a direct target for thyroid hormone in the human brain, and that control of its expression may underlie many consequences of hypothyroidism on mental states during development and adulthood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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