Thermo Fisher Scientific FDPS Recombinant Rabbit Monoclonal Antibody (23GB1395)
FDPS 단백질을 인식하는 토끼 유래 재조합 단일클론 항체로 Western blot, ICC/IF, Flow cytometry에 적합합니다. HEK293F 발현 시스템을 사용하며 고순도 친화 크로마토그래피 정제 방식으로 제조되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB1395 |
| Immunogen | A synthesized peptide derived from human FDPS (370–410AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The isoprene biosynthetic pathway supplies the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate.
Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes.
Liver tissue from patients with peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished FDPS activity and subsequent isoprenoid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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