Thermo Fisher Scientific Phospho-DAPK1 (Ser308) Polyclonal Antibody
DAPK1 단백질의 Ser308 인산화 부위를 표적하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 액상 형태로 제공되며 -20°C 보관. 세포 사멸 및 자가포식 관련 연구에 적합.
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-DAPK1 (Ser308) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DAPK1 around the phosphorylation site of Ser308 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903115 |
Target Information
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor.
DAPK1 participates in multiple signaling pathways regulating cell survival, apoptosis, and autophagy.
It controls both type I apoptotic (caspase-dependent) and type II autophagic (caspase-independent) cell death signals.
DAPK1 phosphorylates PIN1, inhibiting its catalytic activity and nuclear localization, and also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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