Thermo Fisher Scientific FGG Monoclonal Antibody (OTI4D3), TrueMAB
FGG 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, 고순도 친화 크로마토그래피로 정제됨. PBS/BSA/glycerol 완충액에 보관되며, -20°C에서 안정적으로 유지 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D3 |
| Immunogen | Full length human recombinant protein of human FGG produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The FGG gene encodes the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. After vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots. Cleavage products of fibrinogen and fibrin regulate cell adhesion, spreading, vasoconstriction, chemotaxis, and act as mitogens. Mutations in this gene are associated with dysfibrinogenemia, hypofibrinogenemia, and thrombophilia. Alternative splicing produces two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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