Thermo Fisher Scientific C9orf72 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 9-200 of human C9orf72 (NP_0012429831) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C9orf72,uniProtId:Q96LT7-1,ncbiNodeId:9606,antigenRange:9-200,antigenLength:481,antigenImageFileName:PA5-109471_C9orf72_Q96LT7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109471_C9orf72_Q96LT7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.25 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854882

Product Specific Information

Immunogen sequence: SPAVAKTEIA LSGKSPLLAA TFAYWDNILG PRVRHIWAPK TEQVLLSDGE ITFLANHTLN GEILRNAESG AIDVKFFVLS EKGVIIVSLI FDGNWNGDRS TYGLSIILPQ TELSFYLPLH RVCVDRLTHI IRKGRIWMHK ERQENVQKII LEGTERMEDQ GQSIIPMLTG EVIPVMELLS SMKSHSVPEE ID

Target Information

C9orf72 may play a role in endosomal trafficking and autophagy. It is known to interact with HNRNPA1, HNRNPA2B1, UBQLN2, and small Rab GTPSases. C9orf72 localizes in the nucleus, cytoplasm, endosome, lysosome, and autophagosome. Mutations in this gene can result in frontotemporal dementia and/or amyotrophic lateral sclerosis.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.