Thermo Fisher Scientific EPAS1 Monoclonal Antibody (OTI6G3), TrueMAB
인간, 마우스, 랫에서 반응하는 EPAS1 단클론 항체로 Western blot에 적합합니다. 동결건조 형태로 제공되며, 재구성 시 1 mg/mL 농도로 사용 가능합니다. HIF-2 alpha 연구용으로 VEGF 발현 및 혈관 발달 관련 연구에 활용됩니다.
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Applications
- Western Blot (WB): 1:500 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 584–870 of human EPAS1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
HIF-2 alpha (EPAS1) is a transcription factor involved in oxygen-regulated gene expression. It contains a basic-helix-loop-helix domain and a dimerization domain, participating in signal transduction pathways responsive to oxygen levels. HIF-2 alpha regulates VEGF expression and is implicated in blood vessel and lung tubular system development. Mutations in this gene are associated with erythrocytosis familial type 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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