Thermo Fisher Scientific Phospho-CK1 alpha (Tyr321) Polyclonal Antibody
Phospho-CK1 alpha (Tyr321) 폴리클로날 항체로 인간, 마우스, 랫트에 반응합니다. Western Blot, IHC, ELISA에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 저장용액으로 -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Casein Kinase Iα around the phosphorylation site of Tyr321 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4), 0.5% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608684 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, encoding serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric (25–55 kDa) and are found in nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
It can phosphorylate numerous proteins, participates in Wnt signaling, phosphorylates CTNNB1 at Ser-45, and may phosphorylate PER1 and PER2. It may also play a role in chromosome segregation during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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