Thermo Fisher Scientific Phospho-HIST1H2BC (Ser14) Polyclonal Antibody
인간 HIST1H2BC Ser14 인산화 부위를 인식하는 Rabbit Polyclonal 항체입니다. Western blot 및 ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관하며 -20°C 이하에서 안정적입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:1,000
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of Phospho-Ser (14) derived from Human Histone H2B type 1-C/E/F/G/I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.13 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3093662 |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of H2A, H2B, H3, and H4 form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction. The protein also exhibits antimicrobial activity. The HIST1H2BC gene encodes a replication-dependent histone H2B variant located in the large histone gene cluster on chromosome 6, lacking a polyA tail and containing a palindromic termination element.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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