Thermo Fisher Scientific KRT19 Monoclonal Antibody (UMAB3), UltraMAB
KRT19 단백질을 인식하는 UMAB3 클론 단일클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 및 개 시료 반응성. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 용이.
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- pk
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Thermo Fisher Scientific KRT19 Monoclonal Antibody (UMAB3), UltraMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | Assay-Dependent |
| Peptide Array (Array) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB3 |
| Immunogen | Recombinant fragment expressed in E. coli corresponding to amino acids 240–390 of human CK19 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Cytokeratin 19 is part of a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 distinct polypeptides.
Cytokeratins range in molecular weight from 40–68 kDa and isoelectric pH between 4.9–7.8.
Expression patterns of cytokeratin subtypes are used to distinguish epithelial malignancies and assess differentiation status.
Cytokeratin 19 is not expressed in hepatocytes, making it useful for identifying liver metastases.
Cytokeratin antibodies assist in tumor differential diagnosis via immunohistochemistry and are valuable in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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