Thermo Fisher Scientific ARSG Monoclonal Antibody (OTI2A8), TrueMAB
인간 ARSG 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합. TrueMAB 포맷으로 고순도 정제되어 1 mg/mL 농도 제공. PBS/BSA/glycerol 버퍼에 보존되며 -20°C에서 안정적 저장 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A8 |
| Immunogen | Human recombinant protein fragment (aa 17–525 of human ARSG) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They participate in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.
ARSG is a novel arylsulfatase with activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate.
The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum typical of lysosomal sulfatases. It accumulates within lysosomes and functions as a glycoprotein binding specifically to mannose 6-phosphate receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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