Thermo Fisher Scientific ARSG Monoclonal Antibody (OTI4H3), TrueMAB
인간 ARSG 단백질(aa 17-525)에 특이적인 Mouse 모노클로날 항체. Western blot에 1:500 희석으로 사용 가능. Affinity chromatography로 정제된 액상 항체이며, PBS/BSA/glycerol buffer에 보관. -20°C에서 보관, 동결·해동 반복은 피해야 함.
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Applications
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 17–525 of human ARSG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Sulfatases, such as ARSG, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.
This gene, a novel arylsulfatase, has activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate. Activity is competitively inhibited by phosphate.
The unprocessed protein is active as a 63-kDa monomer and demonstrates an acidic pH optimum typical for lysosomal sulfatases. The protein accumulates within lysosomes and is a glycoprotein that binds specifically to mannose 6-phosphate receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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