Thermo Fisher Scientific PUS10 Polyclonal Antibody
Thermo Fisher Scientific PUS10 Polyclonal Antibody는 인간 및 생쥐 PUS10 단백질을 검출하는 고품질 항체입니다. Western blot 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PUS10 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:200–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human pseudouridylate synthase 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636190 |
Product Specific Information
The antibody detects endogenous levels of total PUS10 protein.
Target Information
Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs.
PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable).
It acts as a modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage, and is required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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