
Thermo Fisher Scientific eIF4B Recombinant Rabbit Monoclonal Antibody (7H37L68)
Recombinant rabbit monoclonal antibody specific to human eIF4B. Western blot validated with high specificity and sensitivity. Offers consistent performance through recombinant production. Suitable for research use in multiple species including monkey, ...
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Applications
- Western Blot (WB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7H37L68 |
| Immunogen | Protein corresponding to human eIF4B (aa88–aa178) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2734805 |
Product Specific Information
This antibody is predicted to react with Monkey, Horse, Pig, and Rat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
The eukaryotic translation initiation factor 4B (eIF4B) plays a crucial role in recruiting the 40S ribosomal subunit to mRNA. It functions with eIF4F and eIF4A, binding near the 5′-cap of mRNA in the presence of eIF4F and ATP. eIF4B promotes the ATPase and ATP-dependent RNA unwinding activities of both eIF4A and eIF4F.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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