Thermo Fisher Scientific EEF2K Recombinant Rabbit Monoclonal Antibody (14H7L26)
EEF2K 단백질을 인식하는 토끼 단클론 항체로, Western blot에 최적화됨. 재조합 형태로 높은 특이성과 재현성을 제공. 인간 및 비인간 영장류 반응성. 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host/Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 14H7L26 |
| Immunogen | Protein corresponding to human EEF2K [aa627–aa725] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2762420 |
Product Specific Information
This antibody is predicted to react with Monkey, Cat, and Horse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
EEF2K (Eukaryotic Elongation Factor 2 Kinase) is a highly conserved serine/threonine kinase involved in the calmodulin signaling pathway. Its activity is increased in several cancers, including breast cancer. EEF2K regulates protein synthesis by phosphorylating elongation factor EEF2, preventing it from binding ribosomes and thereby reducing translation elongation rates. Activation occurs via upstream kinases such as AMPK or TRPM7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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