Thermo Fisher Scientific LSM11 Monoclonal Antibody (OTI2A11), TrueMAB

Applications

• Western Blot (WB): 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

LSm11 is a 360 amino acid nuclear protein belonging to the LSm subfamily of snRNP Sm proteins. It contains an N-terminal domain essential for pre-mRNA cleavage and binds specifically to U7 snRNA, playing a role in cell cycle regulation and growth. The LSm11 gene is located on human chromosome 5, which represents about 6% of the human genome. Deletion of the p arm of chromosome 5 causes Cri du chat syndrome, while deletion of the q arm or the entire chromosome 5 is associated with therapy-related acute myelogenous leukemia and myelodysplastic syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.