Thermo Fisher Scientific GABRA5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 32-259 of human GABRA5 (NP_0008011) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GABRA5,uniProtId:P31644-1,ncbiNodeId:9606,antigenRange:32-259,antigenLength:462,antigenImageFileName:PA5-89559_GABRA5_P31644-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89559_GABRA5_P31644-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.78 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805651

Product Specific Information

Immunogen sequence: QMPTSSVKDE TNDNITIFTR ILDGLLDGYD NRLRPGLGER ITQVRTDIYV TSFGPVSDTE MEYTIDVFFR QSWKDERLRF KGPMQRLPLN NLLASKIWTP DTFFHNGKKS IAHNMTTPNK LLRLEDDGTL LYTMRLTISA ECPMQLEDFP MDAHACPLKF GSYAYPNSEV VYVWTNGSTK SVVVAEDGSR LNQYHLMGQT VGTENISTST GEYTIMTAHF HLKRKIGY; Positive Samples: Rat skeletal muscle; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse

Target Information

GABRA5 is a part of GABA, a major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.