Thermo Fisher Scientific CD200R (soluble) Monoclonal Antibody (OX110), Biotin

Applications

• Flow Cytometry (Flow): Assay-dependent

Product Specifications

Additional Formats

• Unconjugated
• FITC
• PE
• Request custom conjugation

Product Specific Information

MA5-17983 targets CD200R/OX-2R in FACS applications and shows reactivity with Mouse samples.
The immunogen used is soluble recombinant mouse CD200R.

Target Information

CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein. Both receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains.
CD200R is restricted to the surfaces of myeloid lineage cells and may function as a myeloid downregulatory signal.
In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leukocytes including T-lymphocytes and mast cells.
Studies suggest that CD200R may control myeloid function in a tissue-specific manner.
Alternative splicing of CD200R results in multiple transcript variants.
Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.