Thermo Fisher Scientific GIT1 Polyclonal Antibody
GIT1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 Immunoprecipitation에 적합합니다. 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 이동 및 시그널링 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Hamster, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the carboxy terminus of human GIT-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 59 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986448 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion, and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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