Thermo Fisher Scientific IL-10 Polyclonal Antibody
Rat IL-10을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ELISA 등 다양한 응용에 적합. 고순도 Protein A/G 정제, 1 mg/mL 농도, PBS buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
- Publications: -
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
- Publications: View 4 publications
ELISA
- Tested Dilution: Assay-dependent
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified recombinant rat IL-10 with full biological activity when compared to standard |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.2 |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536407 |
Target Information
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine regulates immune responses and inflammation by down-regulating Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It promotes B cell survival, proliferation, and antibody production. IL-10 also blocks NF-kappa B activity and participates in JAK-STAT signaling regulation. Mouse knockout studies indicate its essential role in intestinal immune regulation. Mutations in IL10 are linked to increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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