Thermo Fisher Scientific NFE4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NFE4 protein. Validated for Western blot at 1:2,000 dilution. Supplied as liquid form, unconjugated, purified by Protein A and antigen affinity chromatography. Suitable for research use only; store at -20°C fo...
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 135–169 amino acids from the C-terminal region of human NFE4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634904 |
Target Information
Functions as part of the SSP (stage selector protein) complex, which contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR).
The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter.
In contrast, isoform 2 acts as a repressor of gamma-globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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