Thermo Fisher Scientific Transferrin Receptor Monoclonal Antibody (R17217.1.4), PE
PE 형광 표지된 Transferrin Receptor (CD71) 단클론 항체로, Flow Cytometry에 적합합니다. Mouse 시료에 반응하며, Rat IgG2a 아이소타입입니다. 단백질 G 정제, PBS/BSA 완충액에 보관되며 4°C에서 안정적으로 유지됩니다. 연구용 전용 제품입니다.
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Applications
- Flow Cytometry (Flow): Tested at 1.0 µg/1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | R17217.1.4 |
| Immunogen | Induced Friend Erythroleukemia 745.6 cell extracts (Target: Transferrin Receptor (CD71), UniProt ID: Q62351-1, Range: 1–763) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539307 |
Additional Formats
Target Information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome, and in HIV patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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