Thermo Fisher Scientific CD17 Monoclonal Antibody (MEM-68)
CD17 단백질을 인식하는 Mouse IgM 단일클론 항체로, 인간 시료에 반응합니다. Flow Cytometry에 사용 가능하며 1 mg/mL 농도의 액상 형태로 제공됩니다. 세포 분화, 발달, 신호전달 연구에 적합합니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-68 |
| Immunogen | Pre-B cell line NALM-6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | TBS, pH 8 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_11153737 |
Product Specific Information
This antibody recognizes CD17, an extracellular membrane lipid moiety (lactosylceramide) expressed on granulocytes, monocytes, and platelets.
Target Information
CD17 (lactosylceramide) is a ubiquitous glycosphingolipid with an uncharged disaccharide headgroup, highly enriched in lipid raft-derived structures. It plays a key role in the biosynthesis of complex glycosphingolipids and participates in cell-cell and cell-matrix interactions, as well as signaling events involved in differentiation, development, apoptosis, and oncogenesis.
Lactosylceramide regulates integrin functions and nitric oxide production, and its expression defines successive stages in the maturation of myeloid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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