Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI12G7), TrueMAB
PD-L1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. Human CD274(aa 19-290) 재조합 단백질을 면역원으로 제작. 동결건조 형태, PBS 버퍼 및 trehalose 포함. 암 면역회피 연구 및 PD-1/PD-L1 신호 억제 기전 분석에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI12G7), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–290 of human CD274 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Programmed death receptor ligand 1 (PD-L1, also known as B7-H1) is a member of the B7 family.
PD-L1 binds to the programmed death receptor 1 (PD-1), which negatively regulates T-cell receptor (TCR) signaling.
Upon receptor binding, PD-L1 decreases TCR-mediated proliferation and cytokine production.
PD-L1 expression is abundant in many murine and human cancers and can be upregulated by IFN-γ stimulation.
Therefore, PD-L1 plays an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.