Thermo Fisher Scientific HOXD8 Monoclonal Antibody (OTI2A1), TrueMAB
Human 및 Mouse 반응성을 가진 HOXD8 단클론 항체로 Western blot과 IHC(P) 실험에 적합. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 무보존제, 동결건조 형태로 안정적이며 재구성 및 결합 실험에 용이.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 69–290 of human HOXD8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene belongs to the homeobox family of transcription factors, which play essential roles in morphogenesis across multicellular organisms. Mammals possess four similar homeobox gene clusters (HOXA, HOXB, HOXC, HOXD) located on different chromosomes, each containing 9–11 tandemly arranged genes.
The HOXD8 gene is part of the HOXD cluster on chromosome 2. Deletions affecting this cluster have been linked to severe limb and genital abnormalities. Beyond embryogenesis, HOXD8 may also contribute to adult urogenital tract function.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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