Thermo Fisher Scientific HOXD8 Monoclonal Antibody (OTI2A1), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene belongs to the homeobox family of transcription factors, which play essential roles in morphogenesis across multicellular organisms. Mammals possess four similar homeobox gene clusters (HOXA, HOXB, HOXC, HOXD) located on different chromosomes, each containing 9–11 tandemly arranged genes.
The HOXD8 gene is part of the HOXD cluster on chromosome 2. Deletions affecting this cluster have been linked to severe limb and genital abnormalities. Beyond embryogenesis, HOXD8 may also contribute to adult urogenital tract function.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.