Thermo Fisher Scientific Human TICAM2 Synthetic Peptide
Human TICAM2 단백질의 C-말단 13개 아미노산 서열에 해당하는 합성 펩타이드로, PA5-20060 항체의 블로킹 펩타이드로 사용 가능. TLR4의 MyD88 비의존적 신호전달 연구에 활용. 정제된 액상 형태로 제공되며 PBS 버퍼에 0.1% BSA 포함.
- 카탈로그번호
- PEP0179
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the carboxy terminus of human TIRP.
PEP-0179 can be used as a blocking peptide with polyclonal antibody PA5-20060.
Target Information
TRAM, or TRIF-related adaptor molecule (TICAM2), plays an essential role in the MyD88-independent signaling of TLR4.
The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to MyD88-dependent pathway.
Overexpression of TRAM cDNA in endothelial cells reconstituted LPS-induced Trif-dependent NF-kB activation and cxcl10 promoter activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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