Thermo Fisher Scientific HIPK4 Monoclonal Antibody (2E8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

Assay-Dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

2E8

Immunogen

HIPK4 (AAH34501.1, 519 a.a. ~ 616 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HIPK4,uniProtId:Q8NE63-1,ncbiNodeId:9606,antigenRange:519-616,antigenLength:616,antigenImageFileName:MA5-23081_HIPK4_Q8NE63-1_House_mouse.svg,antigenImageFileNamePDP:MA5-23081_HIPK4_Q8NE63-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606557

Product Specific Information

Peptide Sequence: RGSSWEEGEH LGASAEPLAI LQRDEDGPNI DNMTMEAERP DPELFDPSSC PGEWLSEPDC TLESVRGPRA QGLPPRRSHQ HGPPRGATSF LQHVTGHH

Target Information

HIPK4 is a homeodomain-interacting protein kinase and has been demonstrated to phosphorylate p53. HIPK4 encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.