
Thermo Fisher Scientific ITPR3 Polyclonal Antibody
ITPR3 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 시료에 반응합니다. IHC(P)에서 1:200~1:500 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ITPR3. Recombinant protein control fragment (Product #RP-102275) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642828 |
Product Specific Information
Immunogen sequence:
ITSTKNEKIF QESIGLAIHL LDGGNTEIQK SFHNLMMSDK KSERFFKVLH DRMKRAQQET
KSTVAVNMND LGSQPHEDRE PVDPTTKGRV ASFSIPGSSS RYSLGPSLRR GHEVSERVQS
SEMGTSVLIM QPILRFLQLL CENHNRD- Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 89%
Target Information
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus.
Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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