Thermo Fisher Scientific TAS2R41 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TAS2R41, validated for Western blot. Recognizes N-terminal region (aa 14–40). Purified via Protein A and antigen affinity chromatography. Supplied in PBS with sodium azide; suitable for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 14–40 amino acids from the N-terminal region of human TAS2R41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900937 |
Target Information
TAS2R41 is a receptor involved in the perception of bitterness and belongs to the G-protein receptor superfamily. It is expressed mainly in taste receptor cells of the tongue and palate epithelia. The TAS2R41 gene encodes a seven-transmembrane receptor protein and is clustered with eight other taste receptor genes on chromosome 7. Chloramphenicol acts as an agonist for TAS2R41. The receptor may also play a role in sensing the chemical composition of gastrointestinal contents. TAS2R41 activity can stimulate alpha gustducin, mediate PLC-beta-2 activation, and lead to TRPM5 gating. It is expressed in subsets of gustducin-positive taste receptor cells, which can discriminate among bitter stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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