
Thermo Fisher Scientific SF3b145/SAP145 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Immunohistochemistry (IHC)
1:50-1:500
Immunohistochemistry (Paraffin) (IHC (P))
1:100-1:500
Product Specifications
Species Reactivity
Human, Mouse
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 775 and 825 of Human splicing factor 3b, subunit 2, 145kDa (spliceosome associated protein 145). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
SF3B2,
uniProtId:
Q13435-1,
ncbiNodeId:
9606,
antigenRange:
775-825,
antigenLength:
895,
antigenImageFileName:
IHC-00317_SF3B2_Q13435-1_Rabbit.svg,
antigenImageFileNamePDP:
IHC-00317_SF3B2_Q13435-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset and Crab-eating macaque
Target Information
Subunit of the splicing factor SF3B required for A
complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the E
complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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