Thermo Fisher Scientific LXR beta Polyclonal Antibody
Rat LXR beta 단백질을 인식하는 Rabbit polyclonal antibody로 Western blot에 최적화됨. 합성 펩타이드 면역원 사용, 고순도 Affinity chromatography 정제. PBS buffer에 0.09% sodium azide 포함, -20°C에서 보관.
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Thermo Fisher Scientific LXR beta Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of rat LXR beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690299 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%
Target Information
The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.
The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed.
Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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