Thermo Fisher Scientific ABCA7 Polyclonal Antibody
ABCA7 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 마우스 반응성 및 Western blot 검증 완료. 액상 형태로 제공되며, 친화 크로마토그래피로 정제됨. 면역 시스템 지질 항상성 연구에 적합.
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Applications
- Western Blot (WB): Tested Dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse ABCA7 (UniProt ID: Q91V24-1, antigen range: 931–980) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2691030 |
Product Specific Information
This target displays homology in the following species:
- Cow: 93%
- Dog: 100%
- Guinea Pig: 100%
- Human: 100%
- Mouse: 93%
- Rat: 100%
Target Information
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of multiple membrane-spanning domains plus the Walker motifs for the ATP interaction.
ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen, and bone marrow suggest a role in immune system lipid homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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