
Thermo Fisher Scientific ABCB9 Polyclonal Antibody
Human ABCB9 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P)에서 1:20–1:50 희석 비율로 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human ABCB9. Recombinant protein control fragment (Product # RP-95654) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856462 |
Product Specific Information
Immunogen sequence:
ESVGSVYSGL MQGVGAAEKV FEFIDRQPTM VHDGSLAPDH LEGRVDFENV TFTYRTRPHT QVLQNVSFSL S
Target Information
The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of DNA lesions:
- NER (Nucleotide Excision Repair) for UV-induced lesions and bulky chemical adducts
- Recombination repair of genotoxic interstrand crosslinks
NER involves dual incisions on both sides of the damage catalyzed by two nucleases.
In mammalian cells:
- XPG cleaves 3′ of the DNA lesion
- ERCC1/XPF complex makes the 5′ incision
ERCC1/XPF likely plays a role in processing partially processed recombination intermediates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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