Thermo Fisher Scientific ASH2L Polyclonal Antibody
Thermo Fisher Scientific의 ASH2L Polyclonal Antibody는 인간 ASH2L 단백질을 인식하는 토끼 유래 IgG 항체로, Western Blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 284–610 of Human ASH2L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2547772 |
Product Specific Information
- Recommended positive control: HeLa nucleus
- Predicted reactivity: Mouse (99%), Rat (100%), Zebrafish (88%), Pig (100%), Chicken (95%), Chimpanzee (99%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1 (isoform 1), containing a nuclear localization signal and PHD finger motif, suggesting transcription regulatory function.
Predicted molecular weight: 68.7 kDa
Alternative splicing may produce isoforms of 60 kDa and 56.5 kDa.
Human ASH2L shares 60% homology with Drosophila ash2, which regulates gene expression during development, and 90% homology with mouse ASH2L.
ASH2L is expressed mainly in adult heart, testis, and fetal lung/liver, with low expression in adult lung, liver, kidney, prostate, and leukocytes.
Expression varies with differentiation inducers (e.g., phorbol ester, hemin), suggesting roles in hematopoiesis and leukemia.
ASH2L may interact with beta-tubulin and beta-catenin.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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