Thermo Fisher Scientific MYO18A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MYO18A. Recombinant protein control fragment (Product #RP-92100). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYO18A,uniProtId:Q92614-1,ncbiNodeId:9606,antigenRange:138-259,antigenLength:2054,antigenImageFileName:PA5-54328_MYO18A_Q92614-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54328_MYO18A_Q92614-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644360

Product Specific Information

Immunogen sequence: RFSFSQRSRD ESASETSTPS EHSAAPSPQV EVRTLEGQLV QHPGPGIPRP GHRSRAPELV TKKFPVDLRL PPVVPLPPPT LRELELQRRP TGDFGFSLRR TTMLDRGPEG QACRRVVHFA EP

Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

Target Information

MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.