Thermo Fisher Scientific PRP8 Polyclonal Antibody
PRP8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합. Human, Mouse, Rat에 반응하며, 고순도 Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관하며 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: 참고문헌 보기
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: 참고문헌 보기
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PRPF8 (Accession Q6P2Q9), corresponding to amino acid residues I2214–S2264 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854044 |
Product Specific Information
Antibody detects endogenous levels of total PRPF8.
Target Information
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes and is essential for the catalytic step II in the pre-mRNA splicing process. It contains several WD repeats that function in protein–protein interactions. This protein shows sequence similarity to yeast Prp8 and is a candidate gene for autosomal dominant retinitis pigmentosa.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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