Thermo Fisher Scientific RASD2 Monoclonal Antibody (OTI1G1), TrueMAB
RASD2 단백질을 인식하는 마우스 모노클론 항체로, Western blot, IHC, Flow Cytometry 등 다양한 연구용 분석에 적합합니다. 인간 및 개 시료 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 뇌 발달 및 종양 혈관 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G1 |
| Immunogen | Full length human recombinant protein of human RASD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein predominantly expressed in the striatal region of the brain. It belongs to the RASD subfamily of Ras-related GTP-binding proteins and is involved in normal brain development and function. Mice lacking this gene exhibit increased anxiety and motor coordination deficits.
Rhes was identified as TEM2 through analysis of genes upregulated in tumor endothelium. Tumor endothelial markers are significantly increased during angiogenesis and neoangiogenesis, processes crucial for solid tumor growth. TEMs localized on the cell surface and conserved across species are of particular interest for anti-angiogenic therapy development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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