Thermo Fisher Scientific PCMT1 Monoclonal Antibody (OTI2E7), TrueMAB
인간 PCMT1 단백질을 표적으로 하는 마우스 단클론 항체. Western blot에 적합하며, 비결합형 형태로 제공. 고순도 친화 크로마토그래피 정제, 동결건조 상태로 보관. 연구용 단백질 메틸트랜스퍼레이스 관련 실험에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PCMT1 Monoclonal Antibody (OTI2E7), TrueMAB
Thermo Fisher Scientific PCMT1 Monoclonal Antibody (OTI2E7), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 60–285 of human PCMT1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Protein carboxyl methyltransferases are classified into three types based on methyl-acceptor substrate specificity.
Type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These residues arise from spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues, representing covalent damage sites in aging proteins.
PCMT1 (EC 2.1.1.77) acts as a protein repair enzyme that converts abnormal residues back to the normal L-aspartyl form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.