Thermo Fisher Scientific Phospho-Prohibitin (Tyr259) Polyclonal Antibody
Phospho-Prohibitin (Tyr259) 특이성을 가진 Rabbit Polyclonal Antibody로 Western blot에 적합. Human, Mouse, Rat에 반응하며, PBS/glycerol buffer에 보관. 세포 증식 조절 및 종양 억제 연구용으로 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 259 (I-T-Y(p)-L-P) derived from Human PHB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554290 |
Product Specific Information
A suggested positive control for Western blot is MCF-7, PC12, 293 or NIH-3T3 cells.
Target Information
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may function as a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of the 3′ untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3′ untranslated region may act as a trans-acting regulatory RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지: PA5-37682_Prohibitin_P35232-1_Rabbit.svg, PA5-37682_Prohibitin_P35232-1_Rabbit_PDP.jpeg)
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