Thermo Fisher Scientific NENF Polyclonal Antibody
인간 NENF 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 용액 형태로 제공. 신경세포 특이적 단백질 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NENF. Recombinant protein control fragment (Product # RP-94159) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644614 |
Product Specific Information
Immunogen sequence:
LDPADLTHDT TGLTAKELEA LDEVFTKVYK AKYPIVGYTA RRILNEDGSP NLDFKPEDQP
Sequence identity:
- Mouse: 97%
- Rat: 92%
Target Information
NENF is a secreted protein expressed in neurons but not in glial cells of the brain. It has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in astrocytes. NENF activates MAP and phosphatidylinositol-3 kinase pathways, inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting it acts through a Gi/Go-protein-coupled receptor.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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