Thermo Fisher Scientific Importin 7 Polyclonal Antibody
Importin 7 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 polyclonal 항체로, IHC(P) 및 Flow Cytometry에 적합합니다. 다양한 종과 교차 반응성이 예측되며, 핵 내 단백질 수송 연구에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SSFNFGGPAPGMN) corresponding to the C-terminus amino acids of IPO7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10982551 |
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, and rat based on sequence homology.
Target Information
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents activation of Ran’s GTPase by RanGAP1, inhibits nucleotide exchange on RanGTP, and binds directly to nuclear pore complexes where it competes with importin-beta and transportin. It has a Ran-dependent transport cycle and can cross the nuclear envelope rapidly in both directions. Importin beta, transportin, RanBP5, and RanBP7 directly bind and import ribosomal proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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