Thermo Fisher Scientific PAX5 Polyclonal Antibody
PAX5 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체. Western blot 및 Immunocytochemistry에 적합하며, 사람, 마우스, 랫트에 반응. 합성 펩타이드 면역원 기반으로 제작, 액상 형태로 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DLEKNYPTPRTSR) corresponding to the N-terminus amino acids of PAX5 (aa 2–14) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984382 |
Product Specific Information
- This antibody is predicted to react with mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
PAX5 is a member of the paired box (PAX) family of transcription factors. The PAX proteins are crucial regulators in early development, and alterations in their expression are associated with neoplastic transformation.
PAX5, also known as B-cell lineage specific activator protein (BSAP), is expressed at early but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, suggesting roles in B-cell differentiation, neural development, and spermatogenesis.
Mutations in the PAX5 gene can result in leukemia, including acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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