Thermo Fisher Scientific DCK Monoclonal Antibody (OTI16G6), TrueMAB
DCK 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot, IHC, Flow cytometry에 사용 가능. HEK293T 세포에서 발현된 full-length human DCK 단백질로 면역화됨. Lyophilized 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI16G6 |
| Immunogen | Full length human recombinant protein of human DCK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Deoxycytidine kinase (DCK) is an enzyme required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs.
Deficiency of DCK is linked to resistance to antiviral and anticancer agents, while increased DCK activity enhances activation of these compounds into cytotoxic nucleoside triphosphates.
DCK is clinically significant due to its association with drug resistance and sensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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