Thermo Fisher Scientific Monoamine Oxidase B Polyclonal Antibody
Rabbit polyclonal antibody targeting human MAOB, validated for WB, IHC, and ICC. Detects endogenous MAOB levels. Suitable for human, mouse, and rat samples. Supplied as a liquid, 1 mg/mL in PBS with 50% glycerol. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAOB (Accession P27338), corresponding to amino acid residues T327–A377 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900176 |
Product Specific Information
This antibody detects endogenous levels of total MAOB.
Target Information
MAOB (Monoamine Oxidase B), also known as MAO, BRAIN, or AMINE OXIDASE (FLAVIN-CONTAINING) B, is encoded by the MAOB gene in humans. It belongs to the flavin monoamine oxidase family and is located on chromosome Xp11.3.
MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines, playing a critical role in the metabolism of neuroactive and vasoactive amines in both the central nervous system and peripheral tissues.
It preferentially degrades benzylamine and phenylethylamine and also degrades dopamine. MAO-B inhibition increases dopamine activity and reduces hydrogen peroxide production, thereby lowering reactive oxygen species levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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