Thermo Fisher Scientific SCAMP2 Monoclonal Antibody (OTI1H10)
SCAMP2 단백질을 인식하는 Thermo Fisher의 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. Human 시료에 반응하며, Mouse IgG2b 아이소타입. 액상 형태, 1 mg/mL 농도, -20°C 보관. 세포막 단백질 연구 및 막 수송 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H10 |
| Immunogen | Full length human recombinant protein of SCAMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723608 |
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments related to recycling of cell surface receptors and endocytosis. In neurons, they are associated with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs consist of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1–3 contain cytoplasmic N-terminal regions with NPF repeats that interact with EH domain proteins involved in vesicle budding from the plasma membrane or Golgi complex. SCAMPs 4 and 5 lack N-terminal NPF repeats. SCAMPs 1–4 are ubiquitously coexpressed, while SCAMP 5 is brain-specific and expressed late in development, coinciding with the expansion of mature synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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