Thermo Fisher Scientific ABH1 Recombinant Rabbit Monoclonal Antibody (JE56-09)
ABH1 단백질을 인식하는 재조합 Rabbit Monoclonal Antibody(JE56-09). Western blot 및 IHC(P) 검증 완료. Human 및 Zebrafish 반응성. HEK293 발현 시스템 기반, Protein A 정제. 연구용으로 DNA/RNA 손상 복구 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE56-09 |
| Immunogen | Synthetic peptide within C-terminal Human ALKBH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911652 |
Product Specific Information
- Positive Control: Human placenta tissue lysate, MCF-7 cell lysate, Daudi cell lysate, A549 cell lysate, zebrafish tissue lysates, human liver carcinoma tissue, human skin tissue, human small intestine tissue
- Subcellular Location: Mitochondrion, Nucleus
Target Information
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine.
Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate, and iron.
May have a role in placental trophoblast lineage differentiation.
Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-42511_ABH1_Q13686-1_Rabbit.svg, MA5-42511_ABH1_Q13686-1_Rabbit_PDP.jpeg)
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