Thermo Fisher Scientific PAK1 Recombinant Rabbit Monoclonal Antibody (JE57-36)
PAK1 단백질을 인식하는 토끼 유래 재조합 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry에 최적화. 다양한 종(인간, 마우스, 랫트) 반응. Protein A 정제, 1 mg/mL 농도, 장기보관 시 -20°C 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE57-36 |
| Immunogen | Synthetic peptide within human PAK1 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911654 |
Product Specific Information
- Positive Control: HL-60 cell lysates, F9, human lung carcinoma tissue, human stomach carcinoma tissue, mouse brain tissue
- Subcellular Location: Nucleoplasm, Cell membrane, ruffle membrane, Cytoplasm, focal adhesion, invadopodium, Chromosome
Target Information
PAK1 is a serine/threonine kinase that is a target for restenosis, cancer, and immunosuppression treatment. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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