Thermo Fisher Scientific CD138 Recombinant Rabbit Monoclonal Antibody (001)
인간 CD138(Syndecan-1)을 인식하는 재조합 토끼 단클론 항체. ELISA에 최적화되어 있으며, 높은 특이도와 재현성을 제공. 보존제 무첨가 포뮬레이션으로 필요 시 sodium azide 추가 권장. 연구용으로만 사용 가능.
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Applications
Tested Application
- ELISA (ELISA): 1:5,000–1:10,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 001 |
| Immunogen | Recombinant Human Syndecan-1/CD138/SDC1 Protein (Met1–Glu251) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786811 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
This antibody shows specificity for Human Syndecan-1/CD138/SDC1.
Target Information
CD138 (Syndecan-1) is a transmembrane proteoglycan that binds various cytokines and modulates their activity, as well as extracellular matrix components. It influences multiple developmental processes.
- Expressed mainly in differentiating keratinocytes
- Upregulated in the epidermis upon tissue injury
- Highly expressed on plasma cells; also detected on fibroblasts, vascular smooth muscle cells, and endothelial cells
- Expression changes correlate with cancerous transformation
- Soluble sCD138 serum levels serve as a prognostic factor in cancerogenesis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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