Thermo Fisher Scientific C13orf18 Polyclonal Antibody
Human C13orf18 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 40% glycerol buffer에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human C13orf18. Recombinant protein control fragment (Product #RP-102090). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638744 |
Product Specific Information
Immunogen sequence:
AVQVSRRTIS SNSFSPEVFV LPVDVEKENA HFYVADMIIS AMEKMKCNIL SQQQTESWSK EVSGLLGSDQ PDSEMTFDTN IKQESGSSTS SYSGYEGCAV LQVSPVTETR TYHDVKEICK CDVDEFVILE LGDF
Highest antigen sequence identity to the following orthologs:
- Mouse: 54%
- Rat: 49%
Target Information
This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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