
Thermo Fisher Scientific APBA1 Polyclonal Antibody
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APBA1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫에서 반응합니다. WB 및 ICC/IF에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C에 보관하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human APBA1 (Accession Q02410), corresponding to amino acid residues M1–H31 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899492 |
Product Specific Information
Antibody detects endogenous levels of total APBA1.
Target Information
The munc-18 interacting protein (Mint) family is a group of evolutionarily conserved adaptor proteins involved in membrane transport and organization. Mammals have three Mint isoforms: Mint1, Mint2, and Mint3.
- Mint1 and Mint2 are expressed primarily in the brain and bind to Munc18, a key component of the synaptic vesicle fusion machinery.
- Mint3 is ubiquitously expressed at low levels in the brain and testis and does not interact with Munc18.
- Mint3 interacts with the Alzheimer’s disease-related amyloid precursor protein (APP) through its PTB and PDZ domains, linking APP to transport machinery components and regulating its transport, endocytosis, and metabolism.
Abnormal APP metabolism is associated with early-onset Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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