
Thermo Fisher Scientific Gevokizumab Humanized Recombinant Human Monoclonal Antibody
인간화 재조합 단일클론 항체로 IL-1 매개 질환 연구에 사용됩니다. 높은 결합 친화도(300 fM)를 가지며 염증성 사이토카인 조절에 유용합니다. ELISA에 적합하며, CHO 세포에서 발현된 IgG2 카파 아이소타입입니다. 단백질 A로 정제된 액상 형태로 제공됩니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG2, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Immunogen | Human IL1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.31 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.5 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2910873 |
Product Specific Information
- Endotoxin level: < 0.01 EU/µg (LAL method)
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Store at 2–8°C for up to one week.
- Store at -20 to -80°C for up to twelve months from the date of receipt.
Target Information
Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behçet’s Uveitis, Pyoderma Gangrenosum, and Behçet’s Disease Uveitis, among others.
It acts as a modulator of cytokine imbalance in IL-1 mediated disease states and has a very high binding affinity (300 fM), blocking the activation of IL-1 receptors.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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